1
锛?/p>
瀹夊畾娌荤枟鐧棲鍙戜綔鎵�闇�琛�鑽祿搴︿负
0.5-2.5
ug/ml,
宸茬煡
V=60L,t
1/2
=55h.
浠婂
涓�鎮ｈ�?/p>
,
鍏堥潤鑴夋敞灏?/p>
8 mg,
鍗婂皬鏃跺悗浠ユ瘡灏忔椂
8 mg
婊存敞
,
璇曢棶
缁?/p>
2.5
灏忔椂
鏄惁杈?/p>
鍒版不鐤楁墍闇�娴撳害
?
瑙?/p>
:
闈欒剦娉ㄥ皠
30
鍒嗛挓鍚庣殑琛�鑽祿搴︿负
:
C
1
=C
0
e
-kt
=0.1324(mg/L)=0.1324(ug/ml)
鍏朵腑
C
0
=8/60(mg/L) k=0.693/55(h
-1
) t=0.5h
鍦ㄦ鍩虹涓婇潤婊?/p>
2.5
灏忔椂
,
琛�鑽祿搴︿负
:
C
2
=K
0
(1-e
-kt
)(KV)+C
1
e
-kt
灏?/p>
K
0
=8mg/h k=0.693/55(h
-1
) t=2.5h V=60L C
1
=0.1324(ug/ml)
浠?/p>
鍏ヤ笂寮忓緱
C
2
=0.3281+0.1284=0.4565(ug/ml)
鐢变簬姝ゆ椂鐨勮鑽祿搴︿笉鍦?/p>
0.5~2.5 ug/ml
涔嬮棿
,
鎵�浠ヤ笉鍦ㄦ不鐤楄寖鍥村唴
.
鎴?/p>
C
0
e
-k
脳
3
+k
0
/Kv(1-e
-k
脳
2.5
) =0.3281+0.1284=0.4565(ug/ml)
2
锛?/p>
缁欐煇鎮ｈ�呴潤鑴夋敞灏勬煇鑽?/p>
40mg,
鍚屾椂浠?/p>
20mg/ h
閫熷害闈欒剦婊存敞璇ヨ嵂
,
闂粡杩?/p>
4h
浣撳唴琛�鑽祿搴︿负澶氬皯
?(
宸茬煡
V=60L, t
1/2
=40h)
瑙?/p>
:
宸茬煡
,X
0
=40mg, K
0
=20mg/ h, t
1/2
=40h, t=4h, V=60L
鍒?/p>
C
0
=40/60(mg/L) k=0.693/40(h
-1
)
闈欒剦娉ㄥ皠
4
灏忔椂鍓╀綑娴撳害涓?/p>
:
C
1
=C
0
e
-kt
=0.622mg/L=0.622ug/ml
闈欒剦婊存敞缁?/p>
4
灏忔椂琛�鑽祿搴︿负
:
C
2
= k
0
(1-e
-kt
)/Vk =1.288(mg/l)=1.288(ug/ml)
鍥犳
,
缁?/p>
4
灏忔椂浣撳唴琛�鑽祿搴︿负
:
C=C
1
+C
2
=1.910(ug/ml)
3
锛?/p>
鍒╁鍗″洜鐨勬湁鏁堣鑽祿搴︽槸
2.4~6渭g/ml
锛?/p>
濡傚垎鍒互
150mg/h
鍜?/p>
300mg/h
鐨勯�熷害杩涜闈欒剦
婊存敞锛岄棶鏄惁鍚堥�傦紝濡傛灉浣挎偅鑰呯殑绋虫�佽鑽祿搴﹀湪
6渭g/ml
锛屽垯鏈�浣虫淮閫熸槸澶氬皯锛熷凡鐭?/p>
k
=
1.04h-1
锛?/p>
V=40L
銆?/p>
銆愯В銆戜互
150mg/h
閫熷害闈欐淮鏃讹紝绋虫�佽鑽祿搴︿负锛?/p>
mg/L = 3.61渭g/ml